Endocrine Abstracts

Vitamin D deficiency is a worldwide health problem. The lack of appreciation of the importance of sensible sun exposure for providing children and adults with their vitamin D requirement has led to a worldwide vitamin D deficiency pandemic,vitamin D deficiency can have a negative influence on bone development, causing not only rickets, but also interfering with attainment of genetically programmed height.Aim of the study: To assess vitamin D status among...

Background: Type 2 diabetes (T2DM) represents an independent risk factor for cardiovascular diseases (CVD), being characterized by a continuous low-grade inflammation and endothelial activation state. Lipoprotein-associated phospholipase A2 (Lp-PLA2) may have a pro-inflammatory role as growing evidence suggests that it acts in several pathways that contribute to atherogenesis.Objective: The objective is to study Lp-PLA2 a...

Background: Diabetic retinopathy (DR) is a clinically well-defined sight-threatening complication in type 2 diabetes. Angiopoietin 1 (Ang1) has been shown to promote endothelial cell survival without causing proliferation, stabilise endothelial interactions with surrounding support cells and can block the vascular permeability effects of vascular endothelial growth factor (VEGF). More recent data suggest that balance between these growth factors may affect vascular endothelial...